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Renal Considerations When Recommending OTC Analgesics

Renal Considerations When Recommending OTC Analgesics

NSAIDs and Renal Function

See the various ways that NSAIDs may further compromise renal function in kidneys with existing dysfunction.

NSAID inhibition of COX-1 can result in reduced renal profusion in some patients, and its inhibition of COX-2 can affect tubular sodium and water handling.1

McNeil Consumer Healthcare

Reference: 1. DeMaria AN, Weir MR. Coxibs—beyond the GI tract: Renal and cardiovascular issues. J Pain Symptom Manage. 2003;25(2S):S41-S49.